Dry Skin

  • Cream Cleanser - iS CLINICAL Cream Cleanser - iS CLINICAL

    Cream Cleanser

    Regular price $52.00
    Size: 4 fl. oz. e 120 mL
    STEP 1: CLEANSE

    Cream Cleanser

    DEEP-CLEANSING, MOISTURIZING, SOOTHING

    Regular price $52.00
  • Cleansing Complex - iS CLINICAL Cleansing Complex - iS CLINICAL
    Award Winner

    Cleansing Complex

    Regular price $49.00
    Size: 6 fl. oz. e 180 mL
    STEP 1: CLEANSE

    Cleansing Complex

    RESURFACING, CLEARING, DEEP-CLEANSING

    Regular price $27.00 – $49.00
  • Sheald Recovery Balm - iS CLINICAL Sheald Recovery Balm - iS CLINICAL
    Best Seller

    Sheald Recovery Balm

    Regular price $89.00
    Size: Net wt. 2 oz. 60 g
    STEP 2: TREAT

    Sheald Recovery Balm

    PROTECTIVE, SOOTHING, NOURISHING

    Regular price $34.00 – $89.00
  • Hydra - Cool Serum - iS CLINICAL Hydra - Cool Serum - iS CLINICAL
    Award Winner

    Hydra-Cool Serum

    Regular price $108.00
    Size: 1 fl. oz. e 30 mL
    STEP 3: HYDRATE

    Hydra-Cool Serum

    HYDRATING, SOOTHING, CLEARING

    Regular price $70.00 – $108.00
  • Daily Dynamic Hydrator - iS CLINICAL Daily Dynamic Hydrator - iS CLINICAL
    Award Winner
    NB_Award_Seal_2026

    Daily Dynamic Hydrator

    Regular price $135.00
    Size: Net wt. 1.7 oz e 50 g
    STEP 3: HYDRATE

    Daily Dynamic Hydrator

    HYDRATING, DEFENDING, RENEWING

    Regular price $135.00
  • Reparative Moisture Emulsion - iS CLINICAL Reparative Moisture Emulsion - iS CLINICAL
    Best Seller

    Reparative Moisture Emulsion

    Regular price $116.00
    Size: Net wt. 1.7oz e 50 g
    STEP 3: HYDRATE

    Reparative Moisture Emulsion

    RESTORING, HYDRATING, SMOOTHING

    Regular price $116.00
  • Youth Intensive Crème - iS CLINICAL Youth Intensive Crème - iS CLINICAL

    Youth Intensive Crème

    Regular price $256.00
    Size: Net wt. 1.7 oz. e 50 g
    STEP 2: TREAT

    Youth Intensive Crème

    AGE-DEFYING, HYDRATING, FIRMING

    Regular price $256.00 – $420.00
  • Pro - Heal Serum Advance+ - iS CLINICAL Pro - Heal Serum Advance+ - iS CLINICAL
    Best Seller

    Pro-Heal Serum Advance+

    Regular price $177.00
    Size: 1 fl. oz. e 30 mL
    STEP 2: TREAT

    Pro-Heal Serum Advance+

    RESTORATIVE, REVITALIZING, POWERFUL ANTIOXIDANT BLEND

    Regular price $104.00 – $177.00
  • Hydra - Intensive Cooling Masque - iS CLINICAL Hydra - Intensive Cooling Masque - iS CLINICAL

    Hydra-Intensive Cooling Masque

    Regular price $105.00
    Size: Net wt. 4 oz. e 120 g
    STEP 2: TREAT

    Hydra-Intensive Cooling Masque

    REINVIGORATING, REFRESHING, SOOTHING

    Regular price $105.00
  • Warm Up, Cool Down - iS CLINICAL Warm Up, Cool Down - iS CLINICAL
    20% Savings

    Warm Up, Cool Down

    Regular price $125.00
    (20% Savings)
    Size: Boxed Set

    Warm Up, Cool Down

    Regular price $125.00
    (20% Savings)
  • Smooth & Soothe - iS CLINICAL Smooth & Soothe - iS CLINICAL
    21% Savings

    Smooth & Soothe

    Regular price $164.00
    (21% Savings)
    Size: Boxed Set

    Smooth & Soothe

    Regular price $164.00
    (21% Savings)
  • Pure Care Collection - iS CLINICAL Pure Care Collection - iS CLINICAL
    6% Savings

    Pure Care Collection

    Regular price $108.00
    (6% Savings)
    Size: Boxed Set

    Pure Care Collection

    Regular price $108.00
    (6% Savings)
  • Retinol+ Emulsion 0.3 - iS CLINICAL Retinol+ Emulsion 0.3 - iS CLINICAL
    Award Winner

    Retinol+ Emulsion 0.3

    Regular price $117.00
    Size: Net wt. 1 oz e 30 g
    STEP 2: TREAT

    Retinol+ Emulsion 0.3

    AGE-DEFYING, SMOOTHING, BRIGHTENING

    Regular price $117.00
  • Super Serum Advance+ - iS CLINICAL Super Serum Advance+ - iS CLINICAL
    Award Winner

    Super Serum Advance+

    Regular price $177.00
    Size: 1 fl. oz. e 30 mL
    STEP 2: TREAT

    Super Serum Advance+

    RESTORATIVE, SUPER ANTIOXIDANT, REPARATIVE

    Regular price $104.00 – $177.00
  • Extreme Protect SPF 40 - iS CLINICAL Extreme Protect SPF 40 - iS CLINICAL

    Extreme Protect SPF 40

    Regular price $92.00
    Size: Net wt. 3.5 oz. e 100 g
    Tint: Translucent
    STEP 4: PROTECT

    Extreme Protect SPF 40

    ULTRA SHEER, BROAD SPECTRUM, SPF 50+

    Regular price $92.00
  • Warming Honey Cleanser - iS CLINICAL Warming Honey Cleanser - iS CLINICAL

    Warming Honey Cleanser

    Regular price $52.00
    Size: 4 fl. oz. e 120 mL
    STEP 1: CLEANSE

    Warming Honey Cleanser

    DEEP-CLEANSING, MOISTURIZING, SOOTHING

    Regular price $52.00

iS Clinical hydrating skincare products deliver intensive moisture to dry and dehydrated skin with pharmaceutical-grade formulations that restore the appearance of a supple, healthy-looking complexion. Each product in this collection addresses a different dimension of hydration — from cleansing without stripping to deep moisture replenishment and barrier support.

Cream Cleanser offers a gentle, moisture-preserving first step by removing impurities while helping maintain the skin’s natural hydration barrier, making it ideal for dry and sensitive skin types. Reparative Moisture Emulsion is the collection’s cornerstone moisturizer — a lightweight yet deeply hydrating formula combining Hyaluronic Acid with botanical extracts to support the appearance of nourished, resilient-looking skin. 

Hydra-Cool Serum provides a potent infusion of Hyaluronic Acid and botanical antioxidants in an oil-free, cooling formula that can be layered with additional moisture or used alone for lightweight hydration. Ideal for blemish-prone skin, excess sebum, and hot or humid conditions, it delivers a refreshing “drink of water” for the skin without feeling heavy. For intensive barrier support, SHEALD Recovery Balm supports the appearance of a restored, protected skin barrier, while Moisturizing Complex offers rich, emollient hydration for those needing more intensive daily moisture, while Hydra-Intensive Cooling Masque delivers a weekly boost of concentrated hydration.

Dry skin benefits from layered hydration within the Cleanse, Treat, Hydrate, Protect framework. Work with your skincare professional to identify the right combination for your skin's moisture needs. Trusted by professionals in 120+ countries.

Explore moisturizers for additional hydrating options, or find your ideal protocol with the skincare recommendation quiz.