iS Clinical exfoliants are formulated with pharmaceutical-grade ingredients to support the appearance of smoother, more refined-looking skin through controlled resurfacing. Each exfoliator in this collection combines clinical-strength actives with soothing botanicals — delivering visible results without compromising the skin's barrier.

Tri-Active Exfoliating Masque is a multi-action exfoliating treatment that combines enzymatic, chemical, and physical exfoliation in one formula. This versatile masque supports the appearance of refined texture and a brighter, more even-looking complexion with each use. For a professional-level peel experience at home, Active Peel System delivers a two-step chemical exfoliation protocol designed to visibly resurface, smooth and hydrate the skin.

For enhanced brightening, Extra Strength Active Peel Brightening System offers a more intensive resurfacing treatment targeting the appearance of uneven tone, dullness, and textural irregularities. This advanced formula is ideal for consumers seeking visible improvement in skin radiance and clarity.

iS Clinical exfoliants fit within the Treat step of the Cleanse, Treat, Hydrate, Protect regimen. Used 1-3 times per week depending on your skin's tolerance, these formulations complement daily serums and moisturizers for a comprehensive professional-grade skincare regimen. Trusted by dermatologists and estheticians in 120+ countries.

Explore the full serums collection for daily treatment options, or discover your ideal regimen with the skincare recommendation quiz.