Retinol+ Emulsion 0.3

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A Clinically Proven Formula

Our highly effective, fast-acting Retinol+ Emulsion 0.3 formula combines Retinol of botanical origin with a proprietary blend of Bakuchiol, other powerful botanical boosters, antioxidants, and Extremozymes® to help reduce the appearance of fine lines and deep wrinkles while evening skin tone and texture for a smooth, radiant complexion.

We are delighted to offer our professional services to enhance your experience with us. Our team of experts is dedicated to providing you with personalized skincare advice and effective solutions tailored to your unique skin type and needs.

Key Benefits
  • Reduces the appearance of fine lines and wrinkles
  • Diminishes the appearance of uneven skin tones, textures, and blemishes
  • Protects from environmental and oxidative stressors with Extremozyme® technology
  • Strengthens and hydrates the skin
  • Increases firmness and elasticity
  • Glamour South Africa: Beauty Award Winner 2023
How to Use

Apply 2-3 pumps to clean skin, smoothing evenly over face and neck at night every 3 days for 3 weeks. If well tolerated, apply every 2 days or as directed.

This product contains Retinol, which may increase your skin’s sensitivity to the sun and, particularly, the possibility of sunburn. Use sunscreen, wear protective clothing, and limit your sun exposure while using this product and for a week afterward.

Clinically Proven Results
Brightness & Texture After 4 Days
Before After 4 Days
Brightness & Texture
Even Tone After 84 Days
Before After 84 Days
Even Tone
Skin Texture After 84 Days
Before After 84 Days
Skin Texture

What Does Retinol Do?

Retinol is the gold standard in achieving youthful-looking skin. As a form of vitamin A, it increases skin cell turnover to promote firmer, radiant skin. When combined with other botanical ingredients and antioxidants in our unique Retinol+ Emulsion 0.3, it visibly reduces fine lines and wrinkles while smoothing and brightening uneven skin tone and texture.
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Botanically Driven. Science Backed

Crafted with an anti-aging powerhouse formula, Retinol+ Emulsion 0.3 combines Retinol with antioxidants and Extremozymes®. It is the first Retinol cream clinically proven to boost performance while protecting skin health against free radicals and pollutants without irritation.
This nourishing form of Retinol is encapsulated with bio-identical lipids, providing easy delivery to the skin while improving its resilience and overall long-term complexion.
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Skincare with Visible Results

Combining botanically derived Retinol with a proprietary blend of Bakuchiol, other powerful botanical boosters, antioxidants, and Extremozymes®, we've harnessed a powerhouse anti-aging formula that reduces fine lines and wrinkles, boosts hydration, and protects skin health for all.


95% of clinical study subjects reported their skin was smoother after 12 weeks


Clinically proven to help revitalize the appearance of youthful skin


95% of clinical study subjects reported their skin was smoother after 12 weeks

Key Ingredients



A well-delivered botanical form of Retinol that boosts overall skin condition through its vitamin and antioxidant properties.


An ingredient that is even more powerful when combined with Retinol, as it shares the benefits but with higher skin tolerability.


An Extremozyme found in several plants thriving in high-salt environments that helps protect from environmental stressors.
Vitamin C: Bio-available

Vitamin C: Bio-available

A stabilized form of Vitamin C helps protect against environmental stresses and delivers brightening benefits.

Water/Aqua/Eau, Glycerin, Squalane, Pentylene Glycol, Sodium Hyaluronate, Ectoin, Glyceryl Citrate/ Lactate/ Linoleate/ Oleate, Polyglyceryl-4 Cocoate, Polyglyceryl-3 Cocoate, Glyceryl Caprylate, Chlorella Vulgaris Extract, Tocopherol, Butylene Glycol, Bakuchiol, Triethanolamine, Carbomer, Retinol, Phragmites Communis Extract, Poria Cocos Extract, Oryza Sativa (Rice) Bran Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Phosphatidylcholine, Propanediol, Butyrospermum Parkii (Shea) Butter, Polysorbate 20, Caprylic/Capric Triglyceride, Lecithin, Lactic Acid, Polysorbate 40, Helianthus Annuus (Sunflower) Extract, Phenoxyethanol, Polyacrylamide, C13-14 Isoalkane, Laureth-7, Tripeptide-1, Dextran, Ascorbic Acid, Colloidal Gold, Glutathione, Panthenol, Heptyl Undecylenate, C13-16 Isoalkane, Dipotassium Glycyrrhizate, Bidens Pilosa Extract, Elaeis Guineensis (Palm) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Linum Usitatissimum (Linseed) Seed Oil, Glycine Soja (Soybean) Extract, Sodium Hydroxide, Disodium EDTA, Phenylpropanol, Ethylhexylglycerin, Caprylyl/ Capryl Glucoside, Diisopropyl Adipate, Triethyl Citrate, Xanthan Gum, Sorbitol, Fragrance/Parfum

What is the difference between Retinol+ Emulsion 0.3 and Retinol+ Emulsion 1.0?

Both formulas combine Retinol with a proprietary blend of Bakuchiol, our exclusive Extremozyme Technology, and additional antioxidants and botanicals to help reduce the appearance of fine lines and deep wrinkles while evening skin tone and texture for a smooth, radiant complexion.

While both products have similar key ingredients, Retinol+ Emulsion 1.0 is a professional-strength formula that contains a higher concentration of Retinol that is recommended for use as advised by a licensed skincare professional.

How do I know what Retinol+ Emulsion product is best for me?

Your choice will be guided by your desired results, by prior experience with Retinol, and by the advice of your licensed skincare professional. Both products are compounded with the same active ingredients. What makes them different from each other is the concentration of Retinol in each formula.

  • High-performing Retinol+ Emulsion 0.3 is the milder concentration, ideal as a gradual introduction to the formula.
  • Retinol helps balance the skin's complexion and is effective in addressing most of the signs of visible aging. For best results, Retinol+ Emulsion 1.0 should only be used as recommended by a licensed professional.

Do I need a Retinol product in my skincare regimen?

Retinol helps balance the skin's complexion and is effective in addressing most of the signs of visible aging. Although Retinol was originally marketed in the 1940's as an acne treatment, updated research in the 1980's revealed that Retinoids also improve the look of fine lines and wrinkles, dark spots, and other signs of photoaging.

The Clinical Studies performed by an independent facility on our Retinol products showed improvements in:

  • The appearance of fine lines and wrinkles
  • Skin texture
  • Pore size
  • The appearance of post-acne scarring
  • Skin tone and pigmentary irregularities
  • Luminosity
  • Elasticity

What are the benefits of Retinol?

The enriched Retinol+ Emulsion 0.3 & 1.0 formulations help:

  • Reduce the appearance of fine lines and deep wrinkles.
  • Diminish the appearance of uneven skin tone, rough texture, and blemishes.
  • Protect from environmental stressors with Extremozyme technology.
  • Smooth, soften, and brighten complexion.
  • Increase the appearance of skin firmness and elasticity.
  • Provide antioxidant protection to defend against oxidative stressors.

My skin does not show any signs of aging yet. Is it too soon to start using Retinol?

If the skin is healthy and balanced, Retinol can help maintain the skin's natural beauty. Retinol can be a highly effective component in building a preventative skincare regimen that helps prevent signs of future aging.

What are the side effects of Retinol?

Some of the side effects associated with Retinol are:

  • Flaking
  • Temporary or mild redness
  • Irritation
  • Dryness

These are much less common with Retinol+ Emulsion products if application guidelines are followed.

What broad qualities make the Retinol+ Emulsions different?

iS Clinical always uses the best quality ingredients available formulated using the most advanced science and manufactured in our own facility for quality control.

Why is iS Clinical launching a Retinol product now?

Products containing Retinol have been available for decades. However, side effects of redness, flaking, and irritation are commonly associated with these products. iS Clinical patiently awaited the maturation of ingredients and the advancement of scientific formulation, striving for the opportune moment when we could craft an advanced and potent Retinol product. Our goal was to create a solution that optimizes benefits while minimizing potential side effects.

What is the importance of using sunscreen with a Retinol product?

Using SPF with our Retinol+ Emulsion products is essential due to the increased skin sensitivity caused by Retinol. Retinol, a potent derivative of Vitamin A, exfoliates and resurfaces skin, making the skin more vulnerable to sun damage. Sunscreen provides a protective barrier against harmful UV rays, reducing the risk of sunburn, premature aging, and potential long-term skin damage. Combining Retinol with SPF ensures a comprehensive approach to skin health and helps maintain the positive effects of Retinol while safeguarding your skin from environmental stressors.

How should Retinol+ Emulsion be used in a skincare regimen?

Retinol+ Emulsions represent an advanced and targeted solution, formulated to enhance the outcomes of your skincare routine. This exceptional product is particularly beneficial for individuals concerned with signs of aging, blemishes, and hyperpigmentation. To fully capitalize on the advantages of Retinol+ Emulsions, it is vital to follow the comprehensive iS Clinical regimen, encompassing the 4 Steps to Great Skin: CLEANSE, TREAT, HYDRATE, PROTECT.

To maximize efficacy, it is essential for the skin to acclimate to regular exfoliation and proper hydration. Furthermore, daily application of sunscreen is imperative to shield the skin from harmful UV rays. In instances where skin sensitivity is a concern, it is advisable to continue using Pro-Heal Serum Advance+ and/or Poly-Vitamin Serum as alternatives to Retinol+ Emulsions. These options cater to sensitive skin while providing nourishment and desired benefits. Adhering to these guidelines will help achieve optimal results and maintain skin health.

It is always best to consult with a skincare professional regarding your unique skin needs and concerns to design a proper regimen.

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